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1.
Antibiotics (Basel) ; 11(8)2022 Jul 30.
Artigo em Inglês | MEDLINE | ID: mdl-36009894

RESUMO

Inflammations of the facial part of the skull are most commonly caused by a bacterial infection. They are a frequently occurring pathological process, which results from a rich bacterial flora of the oral cavity, as well as diseased teeth and periodontal tissues. These inflammations have a primarily mixed character with the prevalence of anaerobic bacteria. Gangrene of the dental pulp is the most common odontogenic cause. In the case of inflammations of oral tissues an early and corrective treatment results in quick recovery. The purpose of this work was to assess the efficiency of empirical antibiotic therapy applied in patients with inflammations of oral tissues on the basis of a drug susceptibility profile of bacteria isolated from material extracted from inflammatory lesions. The research material consisted of smears collected from patients with existing acute inflammations in the oral cavity. The smear was collected from the bottom of the lesion after its prior surgical treatment and pus evacuation, and again, 7 days after surgery. In patients with acute odontogenic inflammations the recommended first-line therapy are extended-spectrum penicillins, characterized by a low risk of side effects and strong antimicrobial activity. In the study group, both clindamycin and amoxicillin exhibited high efficiency in treating acute odontogenic inflammatory lesions in the oral cavity.

2.
Biomed Res Int ; 2019: 2010453, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31687380

RESUMO

Bacterial infections are the most common cause of purulent soft tissue inflammations in the head and neck area. These bacteria are also responsible for the majority of inflammatory complications after third molar removal. The key to success of antibacterial treatment in both cases is the use of an appropriate antibacterial agent. The aim of the study was to evaluate the susceptibility profile of bacteria isolated from material collected from patients with intraoral odontogenic abscesses. The test material consisted of swabs taken from the odontogenic abscesses, after their incision and drainage. Another swab was collected from the lesion area, 10 days after the initial visit. Results were compared with an identical study conducted on a control group of healthy patients, who had undergone third molar removal. Bacteria identified in this study consisted of aerobic and anaerobic strains, both Gram-positive and Gram-negative. According to the EUCAST guidelines, none of the tested antibiotics was recommended for all identified bacteria. The percentage of bacterial strains sensitive to amoxicillin and clavulanic acid was 78.13% and 81.48% in the study and control groups, respectively, whereas, the percentage of those sensitive to clindamycin was 96.43% and 80.00%, respectively. For Gram-negative aerobic bacteria, gentamicin and ciprofloxacin were among medications affecting all cultured species. 100.00% of strains were found to be susceptible to these antibiotics. Statistically significant relationship between the presence of Gram-negative aerobic strains and the occurrence of complications was found. In the case of the most frequently occurring bacteria in the study, amoxicillin with clavulanic acid and clindamycin were shown to be very effective. In cases of severe purulent odontogenic inflammations, it is recommended to use a combination of antibiotics. Amoxicillin with ciprofloxacin and clindamycin with cefuroxime seem to be the proper choices based on the results of this study.


Assuntos
Antibacterianos/uso terapêutico , Infecções Bacterianas/tratamento farmacológico , Inflamação/tratamento farmacológico , Abscesso/tratamento farmacológico , Abscesso/microbiologia , Adulto , Amoxicilina/uso terapêutico , Infecções Bacterianas/microbiologia , Ácido Clavulânico/uso terapêutico , Clindamicina/uso terapêutico , Feminino , Humanos , Inflamação/microbiologia , Masculino , Testes de Sensibilidade Microbiana/métodos , Pessoa de Meia-Idade , Procedimentos Cirúrgicos Bucais/métodos , Pacientes Ambulatoriais
3.
J Dent Sci ; 12(3): 296-300, 2017 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-30895065

RESUMO

Foreign bodies found in the maxillary sinus include tooth roots, burs, dental impression material, root-filling materials, dental implants, and needles. The purpose of this paper was to present an unusual case of a large foreign body of endodontic origin (root-filling material) removed from the maxillary sinus. A 45-year-old generally healthy male patient reported to the Department of Conservative Dentistry with Endodontics of the Medical University of Silesia, because of orbital and buccal pain on the right side of his face and headaches in the preceding 6 months. Those symptoms were associated with the end of endodontic treatment of teeth 14 and 16. Periapical X-rays, including of teeth 14 and 16, showed the presence of root canal filling with extrusion of endodontic obturation material beyond the apices of tooth 14. In the case of tooth 16, a completely filled palatal canal and incompletely filled buccal canals were found. There was also an irregular dimness at the upper edge of the X-ray image. Panoramic radiography and computed tomography demonstrated a foreign body in the right sinus. Sinus exploration was performed via a surgical procedure conducted using topical anesthesia. The root apices of tooth 14 were resected, and foreign substance was removed. The practitioner did not correctly recognize a complication that occurred during endodontic treatment, which resulted in extrusion of endodontic material beyond the root apices of tooth 14. This case emphasizes the potential impact that an involved maxillary sinus may have on endodontic therapy. Detailed diagnostic identification based on the medical interview, physical and histopathological examinations, and diagnostic imaging allowed rapid surgical intervention and prevented local and general complications. It is important to realize that the range of the periapical X-ray projection is not always sufficient.

4.
Biomed Res Int ; 2015: 869575, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26380300

RESUMO

The aim of this study was to investigate the influence of a topically administered hygienic preparation containing a 3% ethanolic extract of Brazilian green propolis (EEP-B) on oral microflora spectrum changes in a group of patients who underwent common oral surgery procedures. Two gel samples were compared: the tested gel containing an active ingredient, that is, a 3% EEP-B (gel GA), and a placebo as the negative control (gel GC). The collection of microbiological material included 14 patients requiring surgical extraction of wisdom molars and short endosseous implant installation. Clinical examinations were carried out as follow-up, that is, baseline and after 5-6 weeks' time. During the first and subsequent assessment, swabs were taken from the mucosal surface. The number of microorganism species was found to have increased following the application of GC gel over the period of 5-6 weeks. This mainly affected Gram-positive rods and bacilli as well as Gram-negative rods. Application of the GA gel enriched with 3% EEP-B caused a profound reduction in the amount of Neisseria spp. and Bifidobacterium spp. strains. Elimination of seven species of microorganisms was observed: Streptococcus acidominimus, Streptococcus oralis, Staphylococcus epidermidis, Veillonella parvula, Bifidobacterium breve, Bifidobacterium longum, and Lactobacillus acidophilus.


Assuntos
Bactérias Gram-Negativas/efeitos dos fármacos , Bactérias Gram-Positivas/efeitos dos fármacos , Procedimentos Cirúrgicos Bucais , Própole/administração & dosagem , Adulto , Brasil , Etanol/química , Feminino , Humanos , Higiene , Masculino , Pessoa de Meia-Idade , Própole/química
5.
Artigo em Inglês | MEDLINE | ID: mdl-23820707

RESUMO

Autotransplantation is a well-known method used in oral surgery. However, risk of failure, most commonly resulting from root resorption of the transplanted tooth or ankylosis, is quite high. Piezosurgery with specific device tip vibration frequencies enables selective tissue cutting, and therefore, tooth buds or teeth can easily be removed from bones with little injury to periodontal fibers or bud follicles.


Assuntos
Alveolectomia/métodos , Autoenxertos/transplante , Dente Serotino/transplante , Piezocirurgia/métodos , Dente não Erupcionado/cirurgia , Alveolectomia/instrumentação , Regeneração Óssea/fisiologia , Teste da Polpa Dentária , Feminino , Seguimentos , Humanos , Complicações Intraoperatórias/prevenção & controle , Mandíbula/fisiopatologia , Mandíbula/cirurgia , Dente Molar/lesões , Dente Molar/cirurgia , Odontogênese/fisiologia , Planejamento de Assistência ao Paciente , Piezocirurgia/instrumentação , Ápice Dentário/fisiologia , Extração Dentária , Fraturas dos Dentes/cirurgia , Alvéolo Dental/cirurgia , Dente Impactado/cirurgia , Adulto Jovem
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